ANGIOTENSIN CONVERTING ENZYME CSF

General Information

HLAB/HOL Code: ACECF
UPHSM LIS Test #: 8514
Schedule: MONDAY, WEDNESDAY, FRIDAY
Testing Time: 1-5 DAYS
Testing Lab: ARUP Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL CSF
Temperature: Frozen
Tube Type: CSF
Collection Info:
Collect 1 mL of spinal fluid (CSF). Ship frozen.

Specimen Acceptability

Reject Due To

Hemolysis:
NA

Thawing:
Cold OK; Warm reject

Lipemia:
NA

Icterus:
NA

Methods

Quantitative Spectrophotometry

Clinical Utilities

Angiotensin-converting enzyme is increased in some cases of active sarcoidosis. Sensitivity about 75%, specificity about 95%. The sensitivity increases with the stage of the disease. Serial ACE determinations may be helpful in following the clinical course of sarcoidosis or to monitor the effectiveness of corticosteroid therapy. Elevated ACE levels will return to normal in sarcoidosis as a result of spontaneous or corticosteroid-induced remission. Decreased ACE activity is found in patients having chronic obstructive lung disease, lung cancer, emphysema, and cystic fibrosis. Patients with active tuberculosis generally have decreased activity though approximately 6% will show increases in ACE levels.�

CPT Codes

82164

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

0.0-2.5 U/L