APOLIPOPROTEIN A-1 PLASMA

General Information

HLAB/HOL Code: APOA
UPHSM LIS Test #: 7260
Schedule:
Testing Time:
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 2 mL
Temperature: Frozen, Refrigerated, Room Temperature
Tube Type: 1 Red-top, Yellow-top (SST), Green-top (heparin), or Lavender-top (EDTA) tube
Collection Info:
Specimen: Serum (preferred) or plasma

Volume: 2 mL

Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube

Special Instructions: State patient's sex on the test request form.

Collection: Separate serum or plasma from cells. Transfer specimen to a plastic transport tube.

Storage Instructions: Maintain specimen at room temperature.

Patient Preparation: Patient must be fasting 12 to 14 hours.

Causes for Rejection: Specimen from nonfasting patient

Methods

Immunologic


Clinical Utilities

Apo A-1 comprises 60% to 70% of the protein content of HDL. Apo A-1 serves as an activator of LCAT which is involved in the transport of cholesterol from peripheral tissues to the liver where it is degraded. Decreased serum HDL cholesterol levels have been reported to correlate with increased risk of coronary artery disease (CAD); however, Apo A-1 has been suggested as a better discrimination of CAD than HDL.1 Apo A-1 levels also correlate with survival rates or risk factors for patients with myocardial infarction and peripheral vascular disease. Measurement of Apo A-1 may also aid in the diagnosis of Tangier disease (absence of alpha-lipoprotein).

CPT Codes

82172

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Male: 110-180 mg/dL; female: 110-205 mg/dL