AMINOLEVULINIC ACID DEHYDRATASE (ALA-D) WHOLE BLOOD

General Information

HLAB/HOL Code: ALDE
UPHSM LIS Test #: 025980
Schedule: Monday - Friday
Testing Time: 2-4 Days
Testing Lab: Mayo Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: Full 4mL Tube Whole Blood
Temperature: Refrigerated
Tube Type: Sodium Heparin(preferred), Lithium Heparin, or EDTA
Collection Info:
Collection Instructions: Immediately place specimen on wet ice.
Patient Preparation: Abstinence from alcohol is essential for at least 24 hours prior to specimen collection as ethanol suppresses aminolevulinic acid dehydratase (ALAD) activity, leading to false-positive results.
Include a list of medications the patient is currently taking.

Methods

Enzymatic End point/Spectrofluorometric

Clinical Utilities

Preferred confirmation test for the diagnosis of aminolevulinic acid dehydratase deficiency porphyria
This test is not useful for detecting lead intoxication.

CPT Codes

82657

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Reference ranges have not been established for patients who are <16 years of age.

> or =4.0 nmol/L/sec
3.5-3.9 nmol/L/sec (indeterminate)
<3.5 nmol/L/sec (diminished)