FISH ANALYSIS MDS PANEL

General Information

HLAB/HOL Code: FISH
UPHSM LIS Test #: 5436
Schedule: Monday - Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 3.0 mL Bone Marrow or 5.0 mL Blood
Temperature: Ambient
Tube Type: Sodium heparin Bone Marrow or Malignant Blood tube
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of peripheral blood. Draw into green-top (sodium-heparin) tube(s), invert several times to mix. Clotted specimens may not work and can compromise results. Label vial with patient's name and a unique identifying number. Maximum time from collection should not exceed 24 hrs.
SPECIMENS CANNOT BE FROZEN

Methods

Interphase FISH set-up and analysis of 200 cells for EVI1, -5/5q-, -7/7q-, +8, MLL, -20/20q-.

Clinical Utilities

Detection of abnormalities involving -5/5q-, -7/7q-, +8, MLL, Inv(3), and -20/20q- most commonly associated with
myelodysplasia or MDS.

CPT Codes

88271 X 12 DNA Probe, Each
88275 X 4 Interphase in situ Hybridization

As needed CPT codes (at additional charge):
88237 - Cell Culture-BM/Malignant Blood

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.