FISH ANALYSIS AML PANEL
General Information
HLAB/HOL Code: FISH
UPHSM LIS Test #: 5416
Schedule: Monday- Friday
Testing Time: 2 - 7 days
Testing Lab: UP Health System-Marquette
UPHSM LIS Test #: 5416
Schedule: Monday- Friday
Testing Time: 2 - 7 days
Testing Lab: UP Health System-Marquette
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 3.0 mL Bone Marrow or 5.0 mL Blood
Temperature: Ambient
Tube Type: Heparin Bone Marrow or Malignant Blood tube
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert
several times to mix (clotted specimens may compromise results). Label vial with the patient's name and a
unique identifying number (UPHSM encounter # or MR #). Maximum time from collection should be 24 hours.
SPECIMENS CANNOT BE FROZEN
Temperature: Ambient
Tube Type: Heparin Bone Marrow or Malignant Blood tube
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert
several times to mix (clotted specimens may compromise results). Label vial with the patient's name and a
unique identifying number (UPHSM encounter # or MR #). Maximum time from collection should be 24 hours.
SPECIMENS CANNOT BE FROZEN
Methods
Fluorescence in situ hybridization (FISH) Interphase analysis of 200 cells for chromosome -5/5q-, chromosome -7/7q-, MLL rearrangements; 500 cells for RUNX1T1/RUNX1 fusion, PML/RARA fusion and CBFB fusion.
Clinical Utilities
Detection of abnormalities involving chromosome -5/5q-, -7/7q, MLL, INV(16), t(16;16), t(8;21) and t(15;17).
CPT Codes
CALL FOR CPTs
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
An interpretive report will be provided.
