FISH ANALYSIS AML PANEL

General Information

HLAB/HOL Code: FISH
UPHSM LIS Test #: 5416
Schedule: Monday- Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 3.0 mL Bone Marrow or 5.0 mL Blood
Temperature: Ambient
Tube Type: Heparin Bone Marrow or Malignant Blood tube
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert
several times to mix (clotted specimens may not work and can compromise results).  Label vial with the patient's name and a
unique identifying number (UPHSM encounter # or MR #). Maximum time from collection should be 24 hours.
SPECIMENS CANNOT BE FROZEN

Methods

Interphase set-up and analysis of 200 cells for -5/5q-, -7/7q-, MLL; 500 cells for RUNX1T1/RUNX1, PML/RARA and CBFB fusion.

Clinical Utilities

Detection of abnormalities involving 5/5q-, -7/7q, MLL, INV(16), t(16;16), t(8;21) and t(15;17).

CPT Codes

88271 x 12 DNA probe, each
88275 x 7 Interphase in situ Hybridization
88237 (as needed) culture charge.

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.