MULTIPLE SCLEROSIS (MS) PROFILE

General Information

HLAB/HOL Code: MSE
UPHSM LIS Test #: 8680
Schedule:
Testing Time:
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 2.0 (0.8) mL Serum and 1.5 (0.6)mL CSF
Temperature: Refrigerate/Ambient
Tube Type: Serum and CSF collected at the same time
Collection Info:
Collection:  Collect serum and CSF at the same time. Avoid contaminating CSF with blood. Centrifuge CSF at 1500xg for 20 minutes and place the supernatant into separate tubes. Ensure that residual fibrin and cellular matter have been removed.

Causes for Rejection:  Plasma instead of serum specimen; serum and CSF not collected within eight hours of each other

Methods

Oligoclonal banding: IEF; CSF IgG, CSF albumin, and serum IgG: immunologic; serum albumin: spectrophotometry; synthesis rate, ratio, and index by calculation


Clinical Utilities

Adjunct in aiding clinical diagnosis of multiple sclerosis

CPT Codes

82040/Albumin, serum
82042/Albumin, spinal fluid
82784/x2 IgG, serum and spinal fluid
83916

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

See Report