MITOCHONDRIAL (M2) ANTIBODY

General Information

HLAB/HOL Code: MITA
UPHSM LIS Test #: 4694
Schedule:
Testing Time:
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL (0.3 min) serum
Temperature: Room Temperature
Tube Type: : Red-top tube or gel-barrier tube
Collection Info:
Causes for Rejection:  Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added


Methods

Enzyme-linked immunosorbent assay (ELISA)

Clinical Utilities

Use:  The presence of mitochondrial antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of primary biliary cirrhosis (PBC).

Limitations:  The presence of immune complexes in the patient's sample may cause an increased level of nonspecific binding and produce false-positive results. Not all PBC patients are positive for mitochondrial antibodies. Results of this assay should be used in conjunction with clinical findings and other serologic tests.

CPT Codes

83516

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

• Negative: 0.0-20.0

• Equivocal: 20.1-24.9

• Positive: >24.9