MATERNAL SERUM INTEGRATED SCREEN PART II
General Information
HLAB/HOL Code: MSIP2
UPHSM LIS Test #: 025698
Schedule: Daily
Testing Time: 2-5 Days
Testing Lab: Labcorp
UPHSM LIS Test #: 025698
Schedule: Daily
Testing Time: 2-5 Days
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 5.0 (3.0) mL Serum
Temperature: Ambient
Tube Type: Gel-barrier tube
Collection Info:
Collection: Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory. Pour-off is not advised. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
Patient must have submitted a previous specimen in the first trimester for the Maternal Serum Integrated Screening Test Part 1. Gestational age will be based on information provided with the first trimester specimen. Patient information may be provided to the laboratory using the Integrated Serum Form.
Testing provided from 15.0 to 21.9 weeks of gestation.
Temperature: Ambient
Tube Type: Gel-barrier tube
Collection Info:
Collection: Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory. Pour-off is not advised. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
Patient must have submitted a previous specimen in the first trimester for the Maternal Serum Integrated Screening Test Part 1. Gestational age will be based on information provided with the first trimester specimen. Patient information may be provided to the laboratory using the Integrated Serum Form.
Testing provided from 15.0 to 21.9 weeks of gestation.
Specimen Acceptability
Cause for Rejection:
Gross hemolysis; gross lipemia; quantity not sufficient for analysis; improper specimen type
Gross hemolysis; gross lipemia; quantity not sufficient for analysis; improper specimen type
Methods
Chemiluminescent immunoassay
Clinical Utilities
Screening test for open neural tube defects, Down syndrome, and trisomy 18.
Limitations:
Serum integrated screening requires two specimens: one collected in the first trimester and one in the second trimester. This test is for the second trimester portion of the test. This is a screening test. A positive results means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.
Limitations:
Serum integrated screening requires two specimens: one collected in the first trimester and one in the second trimester. This test is for the second trimester portion of the test. This is a screening test. A positive results means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.
CPT Codes
84163
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
Result interpretation will be provided after both 1st and 2nd trimester samples are submitted
