HUMAN EPIDIDYMIS PROTEIN 4 (HE4)

General Information

HLAB/HOL Code: HE4
UPHSM LIS Test #: 026359
Schedule:
Testing Time: 1-3 Days
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 0.8 mL
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
Minimum Volume: 0.4 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.

Specimen Acceptability

Cause for Rejection:
Nonserum sample received

Methods

Electrochemiluminescence Immunoassay (ECLIA)

Clinical Utilities

The assay is used as an aid in monitoring recurrence or progressive disease in patients with epithelial ovarian cancer. Serial testing for patient HE4 assay values should be used in conjunction with other clinical findings used for monitoring ovarian cancer.


Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. This procedure does not provide serial monitoring; it is intended for one-time use only. If serial monitoring is required, please order test 481700. This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

CPT Codes

86305

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

See Report