FISH ANALYSIS EOSINOPHILIA PANEL

General Information

HLAB/HOL Code: FISH
UPHSM LIS Test #: 5436
Schedule: Monday - Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 3.0mL Bone Marrow or 5.0mL Blood
Temperature: Ambient
Tube Type: Sodium Heparin (green top)
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of peripheral blood. Draw into green-top (sodium-heparin) tube(s), invert several times to mix. Clotted specimens may not work and can compromise results. Label vial with patient's name and a unique identifying number. Maximum time from collection should not exceed 24 hrs.
SPECIMENS CANNOT BE FROZEN

Methods

Fluorescence in situ hybridization (FISH) Interphase set-up and analysis of 200 cells each for PDGFRA, PDGFRB and FGFR1/CEP 8; 500 cells for detection of t(16;16) & inversion 16.

Clinical Utilities

Detection of abnormalities involving inversion 16 and t(16;16), trisomy of chromosome 8, deletion of 4q12 CHIC gene, rearrangement of PDGFRA, PDGFRB, FGFR1 genes most commonly associated with myeloproliferative neoplasms.

CPT Codes

CALL FOR CPTs

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.