Antineutrophil Cytoplasmic Antibodies (ANCA) - reflex from VASCU
General Information
HLAB/HOL Code: ANCY
UPHSM LIS Test #:
Schedule:
Testing Time: 3-5 Days
Testing Lab: LabCorp
UPHSM LIS Test #:
Schedule:
Testing Time: 3-5 Days
Testing Lab: LabCorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL
Temperature: Ambient
Tube Type: Serum
Collection Info:
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Temperature: Ambient
Tube Type: Serum
Collection Info:
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Specimen Acceptability
Cause for Rejection:
Gross hemolysis; lipemia; bacterial contamination
Gross hemolysis; lipemia; bacterial contamination
Methods
Indirect fluorescent antibody (IFA)
Clinical Utilities
Antineutrophil cytoplasmic autoantibodies (ANCA) are a serological marker associated with vasculitis and glomerulonephritis. Specifically, ANCA have been found (at frequencies ranging from 70% to 90%) in patients with active Wegener granulomatosis, microscopic polyarteritis nodosa, and idiopathic crescentic glomerulonephritis (with manifestations ranging from kidney-limited disease to extrarenal systemic disease, including pulmonary-renal syndromes). Glomerular lesions in patients with ANCA-associated systemic vasculitis or renal-limited disease are virtually identical. Normal controls are negative for ANCA and <10% of patients with other renal diseases are positive. ANCA may be directly involved in the pathogenesis of the vascular injury that causes the clinical manifestations in ANCA-associated disease.
CPT Codes
86037(x3)
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
