Everolimus, Whole Blood

General Information

HLAB/HOL Code: EVEROL
UPHSM LIS Test #: 026627
Schedule:
Testing Time: 2-4 Days
Testing Lab: LabCorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 2.0 mL
Temperature: Ambient
Tube Type: Whole Blood (EDTA)
Collection Info:
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Lavender-top (EDTA) tube

Methods

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Clinical Utilities

Everolimus is a proliferation signal inhibitor that prevents allograft rejection. It exerts its immunosuppressive effect by inhibiting the proliferation, and thus clonal expansion, of antigen-activated T cells, which is driven by T-cell-specific interleukins. Everolimus inhibits an intracellular signaling pathway that is triggered up binding of these T-cell growth factors to their respective receptors, and which normally leads to cell proliferation. The blockage of this signal by everolimus leads to an arrest of the cells at the G1 stage of cell cycle.

CPT Codes

80169

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.