COAGULATION FACTOR VII ACTIVITY ASSAY PLASMA

General Information

HLAB/HOL Code: FAC7
UPHSM LIS Test #: 029960
Schedule:
Testing Time: 1-3 Days
Testing Lab: Mayo Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL
Temperature: Frozen
Tube Type: Platelet Poor Plasma (sodium citrate)
Collection Info:
Specimen Type: Platelet-poor plasma
Patient Preparation: Patient must not be receiving Coumadin or heparin therapy.
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL

Collection Instructions:
1. Specimen must be collected prior to factor replacement therapy
2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.
3. Aliquot plasma into a plastic vial, leaving 0.25 mL in the bottom of centrifuged vial.
4. Freeze plasma immediately (no longer than 4 hours after collection) at -20 degrees C or, ideally, < or =-40 degrees C.

Additional Information:
1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
2. Each coagulation assay requested should have its own vial.

Methods

Optical Clot-Based

Clinical Utilities

Diagnosing congenital deficiency of coagulation factor VII
Evaluating acquired deficiencies associated with liver disease, oral anticoagulant therapy, and vitamin K deficiency
Determining degree of anticoagulation with warfarin to correlate with level of protein C
Investigation of a prolonged prothrombin time

CPT Codes

85230

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Adults: 65-180%
Normal, full-term newborn infants or healthy premature infants may have decreased levels (> or =20%) which increase within the first postnatal week but may not reach adult levels for > or =180 days postnatal.