ARBOVIRUS ANTIBODY PANEL IGG AND IGM SERUM
General Information
HLAB/HOL Code: ARBVS
UPHSM LIS Test #: 021994
Schedule:
Testing Time: 1-4 Days
Testing Lab: Mayo Labs
UPHSM LIS Test #: 021994
Schedule:
Testing Time: 1-4 Days
Testing Lab: Mayo Labs
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 0.5 mL Serum
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Acceptability
REJECT DUE TO:
Gross hemolysis: Reject
Gross lipemia: Reject
Gross hemolysis: Reject
Gross lipemia: Reject
Methods
Immunoflourescence Assay (IFA)
Clinical Utilities
In patients infected with these or related viruses, IgM class antibody is reliably detected within 1 to 3 weeks of onset, peaking and rapidly declining within 3 months. Results from a single serum specimen can differentiate early (acute) infection from past infection with immunity if IgM is positive (suggests acute infection).
IgG antibody is generally detectable within 1 to 3 weeks of onset, peaking within 1 to 2 months, and declining slowly thereafter. A single serum specimen IgG of 1:10 or greater indicates exposure to the virus. A 4-fold or greater rise in IgG antibody titer in acute and convalescent sera indicates recent infection.
In the United States, it is unusual for any patient to show positive reactions to more than 1 of the arboviral antigens, although Western equine encephalitis and Eastern equine encephalitis antigens will show a noticeable cross-reactivity.
IgG antibody is generally detectable within 1 to 3 weeks of onset, peaking within 1 to 2 months, and declining slowly thereafter. A single serum specimen IgG of 1:10 or greater indicates exposure to the virus. A 4-fold or greater rise in IgG antibody titer in acute and convalescent sera indicates recent infection.
In the United States, it is unusual for any patient to show positive reactions to more than 1 of the arboviral antigens, although Western equine encephalitis and Eastern equine encephalitis antigens will show a noticeable cross-reactivity.
CPT Codes
86651x2/California virus (La Crosse)
encephalitis antibody, IgG and IgM
86652x2/Eastern equine encephalitis
antibody, IgG and IgM
86653x2/St. Louis encephalitis
antibody, IgG and IgM
86654x2/Western equine encephalitis
antibody, IgG and IgM
encephalitis antibody, IgG and IgM
86652x2/Eastern equine encephalitis
antibody, IgG and IgM
86653x2/St. Louis encephalitis
antibody, IgG and IgM
86654x2/Western equine encephalitis
antibody, IgG and IgM
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
CALIFORNIA VIRUS (La CROSSE) ENCEPHALITIS ANTIBODY
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
EASTERN EQUINE ENCEPHALITIS ANTIBODY
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
ST. LOUIS ENCEPHALITIS ANTIBODY
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
WESTERN EQUINE ENCEPHALITIS
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
EASTERN EQUINE ENCEPHALITIS ANTIBODY
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
ST. LOUIS ENCEPHALITIS ANTIBODY
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
WESTERN EQUINE ENCEPHALITIS
IgG: <1:10
IgM: <1:10
Reference values apply to all ages.
Component Info
Name: CALIF VIRUS (LACROSSE) AB IGG SERUM
Method: IFA
CPT Code: 86654
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86654
Ref Range: <1:10
Comp Units: Titer
Name: ST. LOUIS ENCEPH AB IGG SERUM
Method: IFA
CPT Code: 86653
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86653
Ref Range: <1:10
Comp Units: Titer
Name: WEST EQUINE ENCEPH AB IGG SERUM
Method: IFA
CPT Code: 86652
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86652
Ref Range: <1:10
Comp Units: Titer
Name: EAST EQUINE ENCEPH AB IGG SERUM
Method: IFA
CPT Code: 86651
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86651
Ref Range: <1:10
Comp Units: Titer
Name: EAST EQUINE ENCEPH AB IGM SERUM
Method: IFA
CPT Code: 86651-91
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86651-91
Ref Range: <1:10
Comp Units: Titer
Name: WEST EQUINE ENCEPH AB IGM SERUM
Method: IFA
CPT Code: 86652-91
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86652-91
Ref Range: <1:10
Comp Units: Titer
Name: ST. LOUIS ENCEPH AB IGM SERUM
Method: IFA
CPT Code: 86653-91
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86653-91
Ref Range: <1:10
Comp Units: Titer
Name: CALIF ENCEPH AB IGM SERUM
Method: IFA
CPT Code: 86654-91
Ref Range: <1:10
Comp Units: Titer
Method: IFA
CPT Code: 86654-91
Ref Range: <1:10
Comp Units: Titer
