BCR/ABL MRNA DETECTION RT-PCR QUALITATIVE DIAGNOSTIC ASSAY

General Information

HLAB/HOL Code: BCRAQ
UPHSM LIS Test #: BADX
Schedule:
Testing Time: 5-10 Days
Testing Lab: Mayo Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 4.0 mL Whole Blood
Temperature: Ambient or Refrigerated
Tube Type: 1 Lav top EDTA tube
Collection Info:
Specimen must arrive at testing site (Mayo Lab) within 72 hours of collection.
Collection Instructions: Invert several times to mix blood. Send specimen in original VACUTAINERS. Send as soon as possible after collection, on Monday-Thursday only.
Note:
1. The following information is required:
     A. Pertinent clinical history-please confirm that this  test is being ordered for the purposes of making an initial diagnosis
     B. Date of collection
     C. Specimen source (blood)
2. Label specimen appropriately (blood).
Refrigerate specimens must arrive within 5 days of collection, and ambient specimens must arrive with 3 days (72 hours) of collection. Collect and package specimens as close to shipping time as possible.
Volume: 3.0 mL Bone Marrow
Temperature: Ambient or Refrigerated
Tube Type: 1 Lav top EDTA tube
Collection Info:
Specimen must arrive at testing site (Mayo Lab) within 72 hours of collection.
Collection Instructions: Invert several times to mix bone marrow. Send specimen in original VACUTAINERS. Send as soon as possible after collection, on Monday-Thursday only.
Note:
1. The following information is required:
     A. Pertinent clinical history-please confirm that  this test is being ordered for the purposes of making an initial diagnosis
     B. Date of collection
     C. Specimen source (bone marrow)
2. Label specimen appropriately (bone marrow).
Refrigerate specimens must arrive within 5 days of collection, and ambient specimens must arrive with 3 days (72 hours) of collection. Collect and package specimens as close to shipping time as possible.

Methods

RT-PCR

Clinical Utilities

Aids in the diagnostic workup for patients with bcr/abl-positive neoplasms, predominantly CML and ALL
When positive, the test identifies which mRNA fusion variant is present to guide selection of an appropriate monitoring assy.
If a quantitative monitoring assay is not available for a rare fusion variant, this assay may be of some value for monitoring, as it is quite sensitive and can provide a positive or negative result.

CPT Codes

81206
81207
81208

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.