Testosterone Free and Weakly Bound With Total
General Information
HLAB/HOL Code: TESFWT
UPHSM LIS Test #:
Schedule:
Testing Time: 4-6 Days
Testing Lab: LabCorp
UPHSM LIS Test #:
Schedule:
Testing Time: 4-6 Days
Testing Lab: LabCorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 2.0 mL
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Minimum Volume: 1.4 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Collection: Serum should be transferred from cells within one hour of collection and transferred to a plastic transport tube.
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Minimum Volume: 1.4 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Collection: Serum should be transferred from cells within one hour of collection and transferred to a plastic transport tube.
Specimen Acceptability
Cause for Rejection:
Improper labeling
Improper labeling
Methods
Ammonium sulfate precipitation; liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Clinical Utilities
Free and weakly bound testosterone (FWBT), also referred to as bioavailable testosterone, is thought to reflect an individual's biologically active, circulating testosterone. FWBT includes free testosterone and testosterone that is bound to albumin. FWBT does not include sex hormone-binding globulin-bound testosterone. The SHBG-bound fraction is biologically inactive because of the high binding affinity of SHBG for testosterone. The rapid dissociation of "weakly bound" testosterone from albumin results in the availability of essentially all albumin-bound testosterone for steroid-receptor interaction.
CPT Codes
84410
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
