QUAD SCREEN (SECOND TRIMESTER) MATERNAL SERUM
General Information
HLAB/HOL Code: QDSCN
UPHSM LIS Test #: 6634
Schedule: Monday - Saturday
Testing Time: 1 day
Testing Lab: Mayo Labs
UPHSM LIS Test #: 6634
Schedule: Monday - Saturday
Testing Time: 1 day
Testing Lab: Mayo Labs
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL of Serum
Temperature: Refrigerated/ If not tested w/in 7 days, freeze.
Tube Type: Red Top or SST
Collection Info:
1. Do not draw specimen after amniocentesis, as this could affect results.
2. Immediately spin down.
Additional Information:
1. For an assessment that includes neural tube defect results, gestational age must be between 15 weeks, 0 days and 22 weeks, 6 days.
2. Assessments for Down syndrome and Trisomy 18 only are available between 14 weeks, 0 days and 22 weeks, 6 days.
3. Initial or repeat testing is determined in the laboratory at the time of report and will be reported accordingly. To be considered a repeat
test for the patient, the testing must be within the same pregnancy and trimester, with interpretable results for the same tests, and
both tests are performed at Mayo Clinic.
Temperature: Refrigerated/ If not tested w/in 7 days, freeze.
Tube Type: Red Top or SST
Collection Info:
1. Do not draw specimen after amniocentesis, as this could affect results.
2. Immediately spin down.
Additional Information:
1. For an assessment that includes neural tube defect results, gestational age must be between 15 weeks, 0 days and 22 weeks, 6 days.
2. Assessments for Down syndrome and Trisomy 18 only are available between 14 weeks, 0 days and 22 weeks, 6 days.
3. Initial or repeat testing is determined in the laboratory at the time of report and will be reported accordingly. To be considered a repeat
test for the patient, the testing must be within the same pregnancy and trimester, with interpretable results for the same tests, and
both tests are performed at Mayo Clinic.
Methods
Immunoenzymatic Assay
CPT Codes
81511
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
NEURAL TUBE DEFECTS
An AFP multiple of the median (MoM) <2.5 is reported as screen negative. AFP MoMs > or =2.5 (singleton and twin pregnancies) are reported as screen positive.
DOWN SYNDROME
Calculated screen risks <1/270 are reported as screen negative, risks > or =1/270 are reported as screen positive.
TRISOMY 18
Calculated screen risks <1/100 are reported as screen negative, risks > or =1/100 are reported as screen positive.
An interpretive report will be provided.
An AFP multiple of the median (MoM) <2.5 is reported as screen negative. AFP MoMs > or =2.5 (singleton and twin pregnancies) are reported as screen positive.
DOWN SYNDROME
Calculated screen risks <1/270 are reported as screen negative, risks > or =1/270 are reported as screen positive.
TRISOMY 18
Calculated screen risks <1/100 are reported as screen negative, risks > or =1/100 are reported as screen positive.
An interpretive report will be provided.
