General Information

UPHSM LIS Test #: 026346
Testing Time:
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 0.2 mL Serum
Temperature: Frozen
Tube Type: Red-Top(Plain) or Gel-Barrier Tube
Collection Info:
Collection:  Separate serum from cells and transfer to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions:  Freeze

Causes for Rejection:  Gross hemolysis; gross lipemia; icteric specimen; specimens that have thawed in transit; improperly labeled specimen.


Enzyme-linked immunosorbent assay (ELISA)

Clinical Utilities

Establishing the diagnosis of neuromyelitis optica (NMO) and related disorders, including relapsing transverse myelitis or relapsing optic neuritis. Distinguishing NMO and NMO spectrum disorders from multiple sclerosis early in the course of disease. This test can also be used to trigger initiation and monitor effectiveness of therapy.

Limitations:  Seronegativity does not exclude the diagnosis of NMO. Immunosuppressive therapy may result in negative results. Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

CPT Codes


* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

• 0-3.0 U/mL = negative

• 3.1-5.0 = indeterminate (Please submit another sample in six to eight weeks.)

• >5.1 = positive