ACTIN (SMOOTH MUSCLE) ANTIBODY (ASMA)

General Information

HLAB/HOL Code: SMU
UPHSM LIS Test #: 650
Schedule:
Testing Time:
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL Serum (0.3 mL Minimum)
Temperature: Ambient
Tube Type: Red-top tube or gel-barrier tube
Collection Info:
Causes for Rejection:  Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added

Methods

Enzyme-linked immunosorbent assay (ELISA)

Clinical Utilities

Use:  Detection of antibodies aids in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC)

Limitations:  Antiactin antibodies have been reported at low levels in 3% to 18% of sera from the general healthy population. The presence of immune complexes in the patient's sample may produce false positives in this assay. Not all smooth muscle positive samples will have actin antibodies.

CPT Codes

83516

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

• Negative: 0-19

• Weak positive: 20-30

• Moderate to strong positive: >30