MATERNAL SERUM INTEGRATED SCREEN PART I

General Information

HLAB/HOL Code: MSIP1
UPHSM LIS Test #: 5697
Schedule: Daily
Testing Time: 3 days
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 3.0 (1.0)mL Serum
Temperature: Ambient
Tube Type: Gel-Barrier Tube
Collection Info:
Avoid hemolysis. Centrifuge to separate serum. Send complete specimen in the original tube. Do NOT pour off. Maintain specimen at room temperature.
The following information must be provided: gestational age, date on which the patient was the stated gestational age, how gestational age was determined (LMP, EDD, US), patient's race, patient's weight, patient's date of birth, patient's insulin-dependent diabetic status, and the number of fetuses. Also indicate patient history (ie, prior Down syndrome pregnancy, ultrasound anomalies). Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using the Integrated Serum Form. Testing provided from 10.0 to 13.9 weeks of gestation.

Methods

Enzyme Immunoassay (EIA)

Clinical Utilities

Use:
Screening test for open neural tube defects, Down syndrome, and trisomy 18
Limitations:
Serum integrated screening requires two specimens: one collected in the first trimester and one in the second trimester. This test is for the first trimester portion of the test. Result interpretation will be provided only when the second trimester specimen is received and tested. This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine whether a neural tube defect or chromosome abnormality is present.

CPT Codes

84163

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Result interpretation will be provided only when the second trimester specimen is received and tested.