21-Hydroxylase Antibodies
General Information
HLAB/HOL Code: 21HAB
UPHSM LIS Test #: 21HAB
Schedule:
Testing Time:
Testing Lab: LabCorp
UPHSM LIS Test #: 21HAB
Schedule:
Testing Time:
Testing Lab: LabCorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 0.5mL (0.2 min)
Temperature: Frozen
Tube Type: Serum
Collection Info:
Separate serum from cells within one hour. Transfer to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
NOTE: 0.2mL of serum does not allow for repeat testing
Temperature: Frozen
Tube Type: Serum
Collection Info:
Separate serum from cells within one hour. Transfer to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
NOTE: 0.2mL of serum does not allow for repeat testing
Specimen Acceptability
Causes for Rejection: Lipemic or grossly hemolyzed serum samples
Methods
ELISA
Clinical Utilities
Addison's disease (chronic primary adrenal insufficiency) is commonly caused by autoimmune destruction of the adrenal cortex and is characterized by the presence of adrenal cortex autoantibodies in the serum. It can occur sporadically or in combination with other autoimmune endocrine diseases that together comprise Type I or Type II autoimmune polyglandular syndrome. The microsomal autoantigen, steroid 21-hydroxylase enzyme, has been shown to be the primary autoantigen associated with autoimmune Addison's disease. Measurement of 21-hydroxylase autoantibodies aids in diagnosis and management of patients with adrenal insufficiency.
CPT Codes
83516
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
