CEREBROSPINAL FLUID (CSF) IGG INDEX
General Information
HLAB/HOL Code: CSFIG
UPHSM LIS Test #: 029934
Schedule:
Testing Time: 3-6 Days
Testing Lab: Labcorp
UPHSM LIS Test #: 029934
Schedule:
Testing Time: 3-6 Days
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.5 mL
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
BOTH SERUM AND CSF ARE REQUIRED FOR THIS TEST
Minimum Volume: 0.7 mL serum (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
BOTH SERUM AND CSF ARE REQUIRED FOR THIS TEST
Minimum Volume: 0.7 mL serum (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Volume: 1.0 mL
Temperature: Refrigerate
Tube Type: CSF
Collection Info:
BOTH SERUM AND CSF ARE REQUIRED FOR THIS TEST
Minimum Volume: 0.5mL (Note: This volume does not allow for repeat testing.)
Special Instructions: The third tube of a routinely obtained three-tube set of CSF should be used for these studies
Temperature: Refrigerate
Tube Type: CSF
Collection Info:
BOTH SERUM AND CSF ARE REQUIRED FOR THIS TEST
Minimum Volume: 0.5mL (Note: This volume does not allow for repeat testing.)
Special Instructions: The third tube of a routinely obtained three-tube set of CSF should be used for these studies
Methods
CSF IgG, CSF albumin, and serum IgG: immunologic; serum albumin: spectrophotometry; ratio and index by calculation
Clinical Utilities
Use: Detect and measure the level of IgG production by the central nervous
system; has been applied to the diagnosis of multiple sclerosis along with
CSF IgG synthesis rate and CSF immunoglobulin “oligoclonal” bands
Limitations: Conditions in which lymphoreticular elements of the CNS produce
immunoglobulins will result in false-positive (in relation to multiple sclerosis) elevations.
Such conditions include, but are not limited to, aseptic meningitis, lymphoma,
neurosyphilis, Guillain-Barré syndrome, and cerebral lupus erythematosus. These
conditions, however, are either uncommon or are not frequently associated with
an increased IgG index.
system; has been applied to the diagnosis of multiple sclerosis along with
CSF IgG synthesis rate and CSF immunoglobulin “oligoclonal” bands
Limitations: Conditions in which lymphoreticular elements of the CNS produce
immunoglobulins will result in false-positive (in relation to multiple sclerosis) elevations.
Such conditions include, but are not limited to, aseptic meningitis, lymphoma,
neurosyphilis, Guillain-Barré syndrome, and cerebral lupus erythematosus. These
conditions, however, are either uncommon or are not frequently associated with
an increased IgG index.
CPT Codes
82040
82042
82784 (x2)
Test Includes: IgG and albumin quantitation in both serum and spinal fluid; CSF IgG:CSF albumin ratio; CSF IgG index
82042
82784 (x2)
Test Includes: IgG and albumin quantitation in both serum and spinal fluid; CSF IgG:CSF albumin ratio; CSF IgG index
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
